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95% CI, 0.81-0.94) and death from any cause (RR 0.89

In total, 114 core publications were selected, encompassing various interventions, including short-term intensive insulin therapy, non-insulin antihyperglycemic agents (e.g., SGLT-2 inhibitors and GLP-1 receptor agonists), and adjunctive therapies (e.g., vitamin D, sex hormones, and Chinese herbal compounds)

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35 , 713716 (2007) Underwood, C

It says a provider can submit additional clinical evidence, cardiovascular risk scores, or metabolic biomarkers such as HbA1c, a lipid panel, or inflammatory markers, and notes many successful appeals document obesity-related comorbidities or diabetes complications the reviewer initially missed