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Kitzman DW, Brubaker P, Morgan T et al (2016) Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial

How effective is semaglutide GLP-1 for weight loss in non-diabetics

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In rodents, peripherally administrated semaglutide can modulate food preferences by modifying the reward system through dopamine changes in the brain (20)

Weight and HbA1c (in T2D patients) should be monitored every four weeks for the first six months off the drug