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Synoviocytes produce synovial fluid, which functions as a natural biological lubricant and a biochemical pool that allows nutrients and regulatory cytokines to traverse between the joint, thus bearing benevolent properties

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In a study of blood samples from 58 Parkinsons disease patients, they found that glutathione levels not only declined with age, they were also correlated with statistically significant improvements in scores on the Unified PD Rating Scale (UPDRS), which is commonly used to measure Parkinsons disease severity based on patients symptoms, as well as the Patient-Reported Outcomes in PD, another symptom-based scale

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Factors of glutathione deficiency include: Exposure to chemical toxins (including environmental pollution) UV radiation exposure Chronic stress Excessive alcohol use Smoking Poor diet Certain medications And we see the deficiency manifest as wrinkles, inflammation, hyperpigmentation and melasma