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However, these effects are usually subtle and vary significantly from person to person

3.2 Mechanisms of resistance to membrane-targeting antifungals: polyenes and azoles 3.2.1 Polyene antifungal antibiotics interact with cell membrane sterols Polyene antifungal agentssuch as nystatin, AMB, and natamycinare broad-spectrum drugs commonly used to treat opportunistic fungal infections caused by Candida , Cryptococcus , Aspergillus , and Lentinus species (Tugume et al., 2023

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The study was small (only 11 patients total in the treatment group) so authors conclude that larger trials are needed to determine clinical or statistical significance