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Lancet (2019)

It also significantly improved cardiometabolic parameters, including blood pressure, HbA1c, lipids, and C-reactive protein

Dietary salt restriction and potassium supplementation may be necessary

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This polymorphism has been associated with increased risk of benign prostatic hyperplasia and prostate cancer (Rebbeck et al., 1999) and can be a useful biomarker to identify patients at higher risk for fatal prostate cancer (Liu et al., 2013)