After commencement of replacement therapy, once adequate absorption has been confirmed if required, no further monitoring needs to be undertaken and the individual will continue replacement therapy for the duration of their metformin treatment (Stabler, 2013)
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Insulin prepared in neutral solutions containing phenol showed reduced deamidation probably because of its stabilizing effect on the tertiary structure (-helix formation) around the deamidating residue, which lowered the probability for formation of intermediate imides (53)
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Early and late neurodevelopmental influences in the prodrome to schizophrenia: contributions of genes, environment, and their interactions