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Smith SR, Weissman NJ, Anderson CM, et al

Overview of 6 Years Therapy of Type II Diabetes: A Progressive Disease

The FDA has cautioned about "impurities," the use of an untested "salt" form of semaglutide in compounded drugs, and "adverse events," which encompass everything from mild side effects like nausea to life-threatening reactions and even death

doi:10.1016/j.jgr.2020.07.002 Yoon SJ, Kim SK, Lee NY, et al

Potential muscle-related effects include: Improved body composition Reduced visceral fat Mild increases in lean mass In a randomized, placebo-controlled study in HIV-infected adults with abdominal fat accumulation, daily subcutaneous tesamorelin for six months significantly reduced visceral adipose tissue compared with placebo and also increased trunk and total lean body mass, indicating improved overall body composition beyond just weight changes