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Despite promising preclinical data, clinical trials in humans are extremely limited, and the compound remains largely experimental, with ongoing research required to fully characterize pharmacokinetics, optimal dosing, long-term safety, and potential off-target effects.

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Novo Nordisk's oral format is a swallowed tablet, while some compounded options use sublingual administration formats that differ from FDA-approved oral tablets and have not undergone FDA review as finished products

some patients obtain GLP-1s through compounded pharmacy channels or importation, reflecting willingness to switch formulations

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