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Micro-dosing may help with minimizing side effects, or we can explore other routes to ease any discomfort

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This slow titration helps minimize discomfort and ensures that the treatment remains safe and sustainable

Murine models utilising therapeutics of non-mouse origin appear to be poorly representative of irAEs in humans

Docking studies revealed that compounds with aromatic amine residues interact with the large pocket of DPP-4, while compounds with cyclic secondary amine residues bind in the small pocket, similar to Vildagliptin

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