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In a phase 1 trial, a PYY analogue (Y14 peptide) administered subcutaneously at 7- to 14-days intervals was safe and potentially efficacious (WL between 2.9 and 3.6 kg at 31 days, with a 3855% reduction in food intake vs

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45 Clinicians should not limit the use of GLP-1 receptor agonists and deny potential medical benefits to patients because of a history of pancreatitis or a likelihood of developing pancreatitis

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