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Contact your GP if fatigue is severe, significantly impairs daily functioning, persists despite self-management strategies, or is accompanied by signs of dehydration, hypoglycaemia, persistent vomiting, or symptoms suggesting nutritional deficiency such as pale skin or muscle weakness

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This review study highlights the biological effects of different NAD+ boosters as well as the unique benefits of direct NAD+ administration over oral precursors because it bypasses gut and liver metabolism

And of course children, and anyone who is pregnant or breastfeeding

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