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Key Takeaway: Semaglutide primarily works on the digestive system and the brains hunger centers, while topiramate works on the central nervous system to dampen appetite and cravings

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Clinical Trial Registration Number: NCT04841304 Supported by: Rigshospitalet, Augustinus Foundation, Per Henriksen R og Hustrus Fond, Johnny Weilebys Fond, Helen og Ejnar Bjrnows Fond, Region Zealand Disclosure: D