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It contains sterile water mixed with a small amount of preservative

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Vitamin B12 can then be absorbed into the bloodstream via endocytosis in the distal ileum, or by passive diffusion in the absence of intrinsic factor.2 Pernicious anemia (an autoimmune disease) affects the gastric mucosa, leading to destruction of parietal cells and failure to produce intrinsic factor, resulting in vitamin B12 malabsorption and eventually deficiency

The research record is based on animal models and mechanistic reasoning

But there are a few semaglutide-specific considerations

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