Patients using GLP-1 medications alongside insulin or sulfonylureas (e.g., glipizide, glimepiride, glyburide) face an increased risk of hypoglycemia
Enhances collagen type I and III synthesis in injured tendons and ligaments
But there is one group of people who should pay extra attention to protein: those who take GLP-1 drugs (like Ozempic and Mounjaro for type 2 diabetes and Wegovy and Zepbound for weight management)
Insoluble fiber should be introduced cautiously as it may increase bloating and gas in some individuals, potentially compounding tirzepatide's gastrointestinal effects
GLP-1 receptor agonists and the dual agonist tirzepatide modulate appetite, satiety, and gastric emptying, with evidence from STEP (NEJM 2021), SURMOUNT (NEJM 2022), and SURMOUNT-OSA (NEJM 2024)
Summary of key parameters in recent studies generating hepatocyte organoids from tissue-derived human or mouse hepatocytes, in comparison to this study