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The MASLD paper itself noted that reported liver-fat reductions with tirzepatide were lower in prior studies, while also cautioning that differences in population and design limit direct comparison

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What is particularly notable about the CagriSema combination is the much better side effect profile while still retaining body weight loss, comparable to other GLP1R/GIPR dual agonists

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Wegovy supports weight loss by mimicking a hormone called GLP-1 to communicate directly with the brains appetite control centre, the hypothalamus, to lower food-seeking behaviours and hunger

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