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Injury or Trauma Lip biting, burns, or accidental injury may result in a dark black spot on lip due to post-inflammatory pigmentation

We aimed to provide a comprehensive overview of the existing research on the therapeutic effects and underlying molecular mechanisms of TCM and TM, encompassing herbal formulations, single botanical drugs, and their bioactive metabolites

However, successful clinical translation will require a deeper understanding of redox thresholds across cell types, subcellular compartments, and disease stages, as well as strategies to overcome compensatory antioxidant networks and systemic toxicity associated with non-specific redox modulation

S Afr Med J 1983;64:936-41

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