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In a study of over 800 families with melanoma from southern Europe, 3.8% of families who tested negative for CDKN2A and CDK4 pathogenic variants carried POT1 variants.[48] Nine of 14 families had POT1 Ser270Asn variants

Front Oncol 8:617 Venneti S, Dunphy MP, Zhang H et al (2015) Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

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