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This is dangerous because dehydration worsens almost every side effect of the drug, including nausea, fatigue, and constipation

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typically resolving within 1-2 days of implant placement Expected effects : Skin hyperpigmentation at implant site and systemically (expected pharmacological effect) Melanocytic monitoring : Low rates of new nevi (4% versus 2% placebo in Phase 3)

Studies that have used a combination of PARP inhibitors and FK866 have found that this induced lethality in breast cancer cells

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