Dabigatran is a P-gp substrate but is not metabolized by CYP3A4, so the pharmacokinetic concern would be limited to P-gp
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ROS appeared to be closely associated with Bd infection, as DCFH-DA staining was concentrated in cells containing large intracellular zoosporangia (Figure 3D, A2)
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Evaluation of antioxidant capacity of SAC DPPH Free Radical Scavenging Capacity Assay Kit (Nanjing Jiancheng Bioengineering Institute, A153-1-1, Nanjing, China): Prepare the working solution according to the kit instructions, mix with different concentrations of SAC solution, incubate in the dark at 25 for 30 min, centrifuge at 4000 rpm for 5 min, transfer 100L to a cuvette, zero with 80% methanol, and measure absorbance at 517 nm
