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the mitochondrial multienzyme complexes of 2-oxo acids, i.e., of pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH), 2-oxoadipate dehydrogenase (OADH) and branched chain 2-oxo acid dehydrogenase (BCODH), linked to amino acids through their transamination to the 2-oxo acids

Both Eli Lilly and Novo Nordisk have enjoyed explosive earnings growth thanks in large part to the surging popularity of their weight loss drugs: Lillys overall sales rose 28% and net income rose 18% during its most recent quarter on an annual basis, while Novos revenues jumped 36% and profits spiked 60%