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The plasma membrane expression of LAT1 was regained after 3 h of nanoparticle exposure, indicating that the transporter had dissociated from the nanoparticle and relocated on the cell membrane, leaving the nanoparticle to be degraded in lysosomes

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In patients, it was also confirmed that high levels of Arg1 in a G-MDSC population inhibit the proliferation and cytotoxic activity of CD8 + T cells [158]

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L., Klaunig, J