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Ozempic for Weight Loss Because Ozempic can suppress appetite, some people have been taking it off-label as a weight-loss aid

Serious adverse events are rare but can include allergic reactions, vein irritation, or blood pressure changes

Aside from the plate, a balanced gut microbiome enables weight loss and makes it easier to combat side effects such as constipation, which can impact up to 33% of those on some medications

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The human data reflects this advantage, with retatrutide achieving 24.2% weight loss at 48 weeks compared to tirzepatide reaching approximately 21% at 72 weeks in the SURMOUNT trials