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Because NAD+ is a form of vitamin B3-related compound, true allergic reactions are uncommon

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Exercise has been shown to diminish the activity and expression of METTL14 in the thoracic aorta of atherosclerotic mice, thereby inhibiting METTL14-mediated m6A modification on NEAT1 mRNA, which suppresses the expression of NEAT1, and consequently inhibits pyroptosis in ECs to alleviate atherosclerosis (Yang et al., 2023)