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FSP1 at lipid dropletsa new physiological frontier More recent studies have revealed that FSP1 is not restricted to the plasma membrane but can also localize to LDs, where it plays a key role in suppressing lipid peroxidation within stored neutral lipids such as triglycerides and cholesteryl esters

Swap that GLP-1 component for a more potent triple agonist like Retatrutide and the mechanistic ceiling, at least on paper, sits higher still

High glucose levels affect concentrations of glycolytic metabolites, such as lactate, pyruvate, NAD + , and NADH, and consequently affect LDH and MCT activities

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