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Less Mortality with GLP-1 Agonists in Rheumatic Patients Save A recent article in PLOS ONE has shown that treatment of type 2 diabetes (NIDDM) with glucagon-like peptide-1 receptor agonists (GLP-1-RAs) was associated with a significant lowering of risk of all-cause mortality and major adverse cardiovascular events (MACE) in patients with immune-mediated inflammatory diseases (IMIDs) and type 2 diabetes

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While preclinical human studies support its safety and receptor selectivity, caution remains essential due to its systemic effects on metabolism

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