When combined, the SNAC allows oral cyanocobalamin to bypass the usual B12 absorption pathways , which are often impaired in people with B12 deficiency
If side effects do occur, they are generally mild and may include: Pain, discomfort, swelling, or redness at the injection site Diarrhea Headache Bloating Nausea Numbness or tingling Serious side effects are rare and may include: Confusion Dizziness or fainting Muscle pain, cramps, or weakness Extreme thirst Facial flushing Frequent urination Palpitations Fatigue Difficulty breathing Coughing or noisy breathing (wheezing) Extreme pain, swelling, warmth or tenderness in one leg Difficulty swallowing Rash Itching over the body If you experience serious side effects, contact your doctor right away
To prevent any negative effect on sleep, it may be advisable not to take a vitamin B12 supplement at the end of the day
The kidneys are responsible for clearing excess B12 from the blood
How does AOD 9604 work (mechanism of action) While full mechanistic clarity is still under investigation, here are the main proposed/examined pathways: It stimulates lipolysis (the breakdown of stored triglycerides into glycerol + free fatty acids) in fat cells (adipocytes)
This can lead to vitamin deficiency anemia, also known as pernicious anemia