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This is not simply a matter of antioxidant capacity

To understand why this coenzyme is essential for joint health, we must examine its two primary roles in cellular function: Your joints are composed of living tissuesincluding chondrocytes (cartilage cells), synovial membranes, and dense ligamentous structuresthat require cellular energy to maintain their matrix and repair micro-damage

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In trials focused on people with type 2 diabetes, a population already at elevated heart risk, GLP-1s consistently reduced serious cardiovascular events by 1226% depending on the drug and population, with strong results for stroke prevention

Experimental hypothyroid models, including T3/T4 withdrawal and TH receptor (TR/) knockout mice, show spontaneous hepatic collagen accumulation and elevated expression of pro-fibrotic genes, confirming that TH deficiency alone can drive ECM remodeling