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[ CrossRef ] [ Google scholar ] [ PubMed ] Brum AM, Van de Peppel J, Nguyen L, Aliev A, Schreuders-Koedam M, Gajadien T, et al

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a phenomenon characterised by an irreversible cessation in the division of normal cells

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With COMT being responsible for methylating 2-Hydroxyestradiol (2-HE) into 2-ME, it has been demonstrated that low activity or expression of this enzyme could be involved in the pathogenesis of preeclampsia (82)