EVs represent a way for the uterine epithelium to transport nutrients to the growing embryo while protecting them from metabolism by enzymes present in uterine fluid 25
According to the STEP clinical trials referenced in NICE TA875, patients treated with Wegovy achieved substantial weight loss, typically in the range of 10-15% of initial body weight over 68 weeks of treatment when combined with lifestyle interventions
doi: 10.1210/en.2019-00074
J Pharmacol Exp Ther 333:161173 [DOI] [PMC free article] [PubMed] [Google Scholar] Yasumatsu N, Matsuzaki M, Miyazaki T, Noguchi J, Kasai H
What the science says: Because the FDA originally approved sermorelin to treat children with a GH deficiency, medical experts have decades worth of real-world data and clinical use, giving the medication an extremely solid safety profile
It is important to continue to be mindful of proper nutrition while using medications such as GLP-1 & GIP therapy to help lose fat and maintain lean muscle mass, which is vital for your overall metabolic health