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Epub 2022 Jan 21

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Kelly J, Fulford J, Vanhatalo A, Blackwell JR, French O, Bailey SJ, Gilchrist M, Winyard PG, Jones AM

RNA Isolation Cells were washed with PBS without Ca 2+ and Mg 2+ (Sigma) and each sample (1 10 6 cells) was lyzed with 1 ml QIAzol (QIAGEN)

Given their biological antioxidant function, the antioxidant genes in the glutathione S-transferase (GST) family are believed to be associated with development and progression of asthma

To test this, we employed a mouse model with a double Glp-1r and Gipr KO and a pharmacological approach using the specific GLP-1R antagonist exendin-3