We at Rasa Derm think that you should love your natural skin tone and make it clearer, more hydrated, and more radiant in a safe and ethical way
Use sunscreen year-round on areas of the skin that are regularly exposed to sunlight, such as your face and hands
A typical titration schedule might look like this: Weeks 1-4: 0.125 mg twice weekly (0.25 mg total) Weeks 5-8: 0.25 mg twice weekly (0.5 mg total) Weeks 9-12: 0.5 mg twice weekly (1.0 mg total) Weeks 13-16: 0.85 mg twice weekly (1.7 mg total) Weeks 17+: 1.2 mg twice weekly (2.4 mg total) This approach extends the time at each dose level compared to standard titration
Semaglutide belongs to a group of drugs called glucagon-like peptide 1 receptor agonists (GLP-1 receptor agonists)
Therefore, it is generally not recommended in these populations
For example, CD40 agonism reprograms TAMs via FAO- and ACLY-mediated epigenetic rewiring, enabling robust M1-like polarization even in a glucose-deprived TME [173]
