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These rings develop when copper accumulates in the eye
Funding This work was supported by the National Natural Science Foundation of China (8247143079), The Discipline Construction Project of Hunan University of Chinese Medicine (Z2023JBGS05), the Key Project of Education Bureau of Hunan Province (23A0293), the Hunan Province Science and Technology Innovation Leading Talent Project (2021RC4034), the Key Project at Central Government Level: the ability establishment of sustainable use for valuable Chinese medicine resources (2060302)
Gene knockdown or overexpression Small interfering (si)RNA (GenePharma, Shanghai, China) or short hair (sh)RNA (Genechem) was transfected for knockdown of VDAC1 ( Table S2 )
It plays a key role in tissue repair, inflammation regulation, and protection of the gastrointestinal tract
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