However, BCG is associated with severe adverse effects, including acute toxicities (dysuria, hematuria, fever, bladder irritation) and delayed toxicities (flu-like symptoms, pneumonia, hepatitis, granulomatous prostatitis) 81
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Overall survival benefit with tebentafusp in metastatic uveal melanoma
To determine whether these parameters were affected by exogenous IGF-1 during NEC development, neonatal mice were injected with recombinant IGF-1 (50 g/kg/day) or vehicle control twice daily and submitted to an NEC model for 24 h