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However, the heat generated by the therapy is difficult to control, which may trigger high-temperature damage to nearby organs or tissues

(Figure 3) Some studies have shown that Nox is involved in macrophage phagocytosis and neutrophil bactericidal activity, so Nox has a firmly established importance in immune function ( 2 and H 2 O 2 produced by Noxs in many cell types are essential for normal signal transduction of growth factors and cytokines ( 2 and H 2 O 2 (Morel et al., 2015)

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doi: 10.1016/j.micpath.2021.105216 256 HamerHMJonkersDMVanhoutvinSATroostFJRijkersGde BruneAet al

The conundrum of exercise for weight management in the GLP-1 receptor agonist era