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These medications are not generally recommended while pregnant or breastfeeding

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Given concerns about long-term therapeutic impact, PRO objectives related to tolerability may be especially salient for post-treatment data collection

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Participants without diabetes achieved average weight losses of 1518% at the highest doses, with improvements in blood pressure, cholesterol, and inflammatory markers

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Cell Metab (2020) 32:676688.e4

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If side effects persist, glucose control is inadequate, or progress stalls, the post directs the reader to discuss adjustment strategies with a healthcare provider

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