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Lancet 2006;368:1795-1809

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Patients typically see: 4% body weight reduction after two months 6% reduction after three months 8% reduction after four months Long-term Results (Beyond Week 20) Extended treatment shows impressive outcomes: Average weight loss of 15% by month 17 Sustained results through continued treatment Improved metabolic health markers You should take a missed dose within five days for the best results

Both formulations share the same active amphetamine salts and a similar side effect profile, including appetite suppression, dry mouth, insomnia, and headaches, but IR side effects tend to be more intense and short-lived, while XR side effects onset more gradually and taper more smoothly

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