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The requirement of two distinct glutathione interaction sites for the efficient reduction of GSSR by GSH explains the deviating properties and substrate preferences of glutaredoxin subfamilies as well as thioredoxins with implications for the design and optimization of artificial enzymes and inhibitors

General guidelines include: Store in a cool, dry location before opening Keep away from direct sunlight Avoid contamination of the rubber stopper Use sterile handling techniques when withdrawing liquid Always inspect the solution before use

575 Fronto-temporal dementia, FTD The role and contribution of astroglia to FTD remains largely unexplored

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