[12] [13] Diagnosis involves excluding other conditions that might explain the symptoms, with basic investigations such as full blood count, inflammatory markers (ESR/CRP), thyroid function, and vitamin D levels often considered
Adipose tissue (body fat) is not metabolically inert
This meant GLP-1 would need to be given in high doses if it was to have any therapeutic potential
All clinical trials for dementia outcomes identified by our search 42,43,44 had been included in the meta-analyses above
GLP-1 improves the neuronal supportive ability of astrocytes in Alzheimers disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway
Moreover, the regulatory frameworks for innovative multi-target therapies are complex, necessitating extensive safety databases including varied patient demographics