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The FDA issued a safety alert in April 2025 noting 32 adverse event reports (20192024) including erectile dysfunction, depression, and suicidal ideation

Newer studies that have come out do suggest that there is a real connection between thyroid cancer and the long-term use of GLP-1 agonists

We now know that certain keystone strains of bacteria in your gut are directly connected to your bodys natural GLP-1 production

10.1007/s12325-022-02153-x 42 KangX.WangD.ZhangL.HuangT.LiuS.FengX.et al (2023)

Perineuronal nets (PNNs) are well organized structures formed by extracellular matrix molecules condensed around cell body and proximal dendrites of some types of neurons (Kwok et al., 2011)