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The principal serious adverse reactions are: (1) Ovarian hyperstimulation, a syndrome of sudden ovarian enlargement, ascites with or without pain and/or pleural effusion, (2) Rupture of ovarian cysts with resultant hemoperitoneum, (3) Multiple births and (4) Arterial thromboembolism

Inhibition of human organic anion transporter 3-mediated pravastatin transport by gemfibrozil and its metabolites in humans

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The reason storage discipline matters more here than for a single-use peptide is arithmetic: because one vial spans several once-weekly doses over potentially a month, the solution has to hold potency across that entire window