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It also inhibits excessive cell proliferation, promotes cell apoptosis ( In experiments with nave CD4 + T cells isolated from the spleen of C57BL/6 mice, catalpol downregulates the levels of glycolysis products pyruvate and lactate by suppressing the expression of pyruvate kinase M2 (PKM2) and LDHA

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Zou MH, Shi C, Cohen RA

-MSH itself is posited to be a naturally produced peptide hormone

Journal Reference : Fares Qeadan