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To address the challenges mentioned and promote the clinical translation of ROS-targeted agents, we could improve drug absorption and distribution by optimizing the chemical structure of the drug or using delivery systems like nanoparticles

doi: 10.1158/1078-0432.CCR-16-1924 332 SharmaAKoldovskyUXuSMickRRosesRFitzpatrickEet al

These insights could clarify whether restoring CBF alone is sufficient for symptom recovery or if targeting astrocytic GABA remains essential for addressing inhibitory dysfunction

Oxidative stress is a state of imbalance between the production of free radicals and the body's ability to neutralize them

aeruginosa mutant strain deficient in both gshA and gshB showed a 4-fold and 8-fold increase in sensitivity to hydrogen peroxide and superoxide, respectively, suggesting antioxidant defense of GSH on antibiotics

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