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Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease

Mechanistically, GPX4 inhibition in HK-2 cells triggers iron-dependent release of pro-necrotic mediators that promote fibroblast proliferation and myofibroblast differentiation, effects reversed by Lip-1 (189)

doi: 10.1038/s41419-020-2298-2 34 LiD.LiY

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