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What we know Some, but not all, observational studies have associated high caffeine consumption (350-699 mg/day) with adverse effects during pregnancy, such as an increased risk of miscarriage and delivering a low-birth-weight baby

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It is supplied for use in controlled laboratory environments to support the preparation, dilution, and handling of research compounds under aseptic conditions

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Indeed, ASD, although known by other labels over time [42], has consistently been distinguished by a deficit in social awareness [43] and was viewed as rare by knowledgeable individuals in the US and independently in Europe at the time of its discovery 80 years ago [44,45]