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Beyond its metabolic benefits, semaglutide treatment significantly improved nest-building performance in Bbs5 / mice (Figure 5I)

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In Ohio, a bipartisan bill introduced in July (HB 388) would allow state employees to receive reimbursement for GLP-1 drugs

The liver's metabolic capacity is the rate-limiting step, not the rate of drug delivery

These are not FDA-approved medications but are available as dietary supplements

Bbs5 / mice exhibit significant visual impairments due to retinal degeneration, including a complete loss of cone photoreceptor function and reduced rod function, as evidenced by structural abnormalities in the outer nuclear layer and mislocalization of photoreceptor proteins