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Collectively, these studies support the versatile antibacterial potential of CQDs through various mechanisms, however, most evidence remains derived from in vitro systems, with limited in vivo validation and safety profiling, highlighting the need for further evaluation prior to clinical translation

in Regulatory Toxicology and Pharmacology confirmed the favorable safety profile of this compound across multiple evaluated parameters

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Supplemental Figs

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Finally, avoid metallic applicators that could leach ions and disrupt the copper complex