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Additionally, studies employing cortical pattern matching have shown diminished cortical gray matter thickness in the left anterior cingulate cortex among individuals with T2DM, with those co-diagnosed with major depression exhibiting significant cortical gray matter reductions in bilateral prefrontal areas when compared to healthy controls [102]

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Heres what you need to know: The FDA approved the once-daily Wegovy pill (25 mg) on December 22, 2025