Supplementary Information Additional file 1: Video 1
Oncology includes Verzenio, which generated $1.47 billion in Q3 2025, along with Jaypirca, Retevmo, Cyramza, and the recently approved Inluriyo for HRpositive, HER2negative breast cancer
Based on potential binding regions predicted by JASPAR database, we designed specific primers targeting the binding site between c-Myc and the miR-29b-3p promoter (Table S2)
Mice in NM group received adenine suspension at a dosage of 50 mg/(kgday) by gavage, 0.4 mL/time, once a day for 14 days, and Folium sennae decoction at a dosage of 10 g/(kgday) by gavage, 0.4 mL/time, once a day for 7 days, starting on 8th day
As of June 2026, tesamorelin is FDA-approved only for HIV-associated lipodystrophy (sold as EGRIFTA WR and EGRIFTA SV), ipamorelin is not FDA-approved, and the blend is not FDA-approved
Next came drugs like Zepbound and Mounjaro, which contain the drug tirzepatide