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Countries in Sub-Saharan Africa, the Middle East, and Latin America will be particularly affected by this surge

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These considerations suggest that GLP-1RA biology is best interpreted within a broader metabolic context in which substrate availability, redox buffering capacity, and tissue-specific energetic constraints shape systemic adaptation to sustained pharmacological weight reduction

Medicare coverage expansion for weight management would generate approximately $66 billion in spending over ten years, with estimated savings of $18 billion through reduced hospitalizations and chronic disease management

Obesity in children is a risk factor for adult MetS (17)