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If symptoms persist despite these measures, discussing dose adjustment or slower titration with your healthcare provider is appropriate

Outcomes The primary outcome in our network meta-analysis was MACE, defined as the composite of cardiovascular mortality, nonfatal myocardial infarction (MI), and nonfatal stroke

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Onishi J, Meinz M, Thompson J, Curotto J, Dreikorn S, Rosenbach M, Douglas C, Abruzzo G, Flattery A, Kong L

[DOI] [PubMed] [Google Scholar] 84.Smeland O.B., Meisingset T.W., Borges K., Sonnewald U

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